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But further B vitamins are also (indirectly) essential for homocysteine degradation: Vitamin B2, for instance, is present in the reaction of 5,10-methyleneTHF into 5-methyltetrahydrofolate (5-MeTHF) by methylenetetrahydrofolate reductase (MTHFR)

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JPH203 is an inhibitor of SLC7A5 and is a compound designed on the basis of the conformational relationship of the SLC7A5 ligand